COVID-19 Three-Dose Vaccine Series for Immunocompromised Individuals Available Now
The Alaska Department of Health and Social Services (DHSS) is encouraging all Alaskans who are immunocompromised to follow a national recommendation to get a three-dose vaccine series now and is also closely following news about a federal plan to offer booster doses starting in late September to all

The Alaska Department of Health and Social Services (DHSS) is encouraging all Alaskans who are immunocompromised to follow a national recommendation to get a three-dose vaccine series now and is also closely following news about a federal plan to offer booster doses starting in late September to all Americans who are already fully vaccinated with an mRNA vaccine (Pfizer or Moderna) according to a press release issued today.
The federal recommendation for a three-dose primary mRNA vaccine series for immunocompromised individuals was based on studies showing that many immunocompromised people are unable to mount a robust enough immune response after the initial two-dose primary mRNA vaccine series is completed. The additional dose reinforces and helps build the immune response to provide an acceptable level of effectiveness against potential COVID-19 infection.
Alaska DHSS notes that this additional mRNA dose in a primary series should not be confused with a booster dose. Third doses are available to moderately or severely immunocompromised persons throughout the state anywhere COVID-19 vaccines are provided.
Moderately to severely immunocompromised individuals include people who have:
- Been receiving active cancer treatment for tumors or cancers of the blood
- Received an organ transplant and are taking medicine to suppress the immune system
- Received a stem cell transplant within the last 2 years or are taking medicine to suppress the immune system
- Moderate or severe primary immunodeficiency (such as DiGeorge syndrome, Wiskott-Aldrich syndrome)
- Advanced or untreated HIV infection
- Active treatment with high-dose corticosteroids or other drugs that may suppress the immune response
More information on the CDC’s recommendation for immunocompromised individuals is available online. The CDC’s joint statement with the U.S. Department of Health and Human Services about planning for booster shots is also available online.
The press release can be found below.